Dataset
550 traditional Chinese medicines, 10936 components, 2527 targets, 465 targets of 40 pharmacological effects, ,18 efficacies and 18 properties information were collected and processed from Chinese pharmacopoeia, DrugBank, CTD, HIT. TCMBank and literature.
Identifying Pharmacological Effects
Literature data was collected using a web crawler framework, and a identification model of pharmacological efficacy based on the GoogLeNet architecture was subsequently developed.
Identifying Efficacy and Property of TCM Components
Based on the 40 pharmacological features of 550 Chinese herbal medicines, 34 recognition models for efficacy and medicinal properties were established using a multi-algorithm optimization framework built on Optuna.
Application of SYSTCM
The SYSTCM platform can be utilized for investigating associations among active ingredients, constituents, and the multi-level relationships between components, targets, pharmacological effects, efficacies, and medicinal properties in traditional Chinese medicine, thereby providing new insights into mechanisms of action and efficacy discovery.